Naphthoquinones may cause oxidative stress in exposed cells and, therefore, affect redox signaling.Here, contributions of redox cycling and alkylating properties of quinones (both natural and synthetic, such as plumbagin, juglone, lawsone, menadione, methoxy-naphthoquinones, and others) to cellular and inter-cellular signaling processes are discuss
A Terahertz-Microfluidic Chip with a Few Arrays of Asymmetric Meta-Atoms for the Ultra-Trace Sensing of Solutions
Biosensing with terahertz (THz) waves has received large amounts of attention due to its potential to detect the functional expression of biomolecules in a label-free fashion.However, many practical challenges against the diffraction limit of THz waves and the strong absorption of THz waves into polar solvents still remain in Wallet the development
Understanding the mix of services for mental health care in urban DR Congo: a qualitative descriptive study
Abstract Background Mental health workers (MHWs) are exposed to conflicts of competence daily when performing tasks related to the provision of mental health services.This may be linked to a lack Rompers of understanding of their tasks as caregivers and providers.Furthermore, in most low-income settings, it is unclear how the available services are
The Microtubule Minus-End Binding Protein Patronin Is Required for the Epithelial Remodeling in the Drosophila Abdomen
In the developing Drosophila abdomen, the epithelial tissue displays extensive cytoskeletal remodeling.In stark contrast to the spatio-temporal control of the actin cytoskeleton, the regulation of microtubule architecture during epithelial morphogenesis has remained opaque.In particular, its role in cell motility remains unclear.Here, we show that
Artificial intelligence in melanoma diagnosis: Three scenarios, shifts in competencies, need for regulation, and reconciling dissent between humans and AI
Tools based on machine learning (so-called artificial intelligence, AI) are increasingly being developed to diagnose malignant melanoma in dermatology.This contribution discusses (1) three scenarios for the use of AI in different medical settings, (2) shifts in competencies from dermatologists to non-specialists and empowered patients, (3) regulato